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Date: 30-11-2021
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Sphingophospholipids
The backbone of sphingomyelin is the amino alcohol sphingosine, rather than glycerol (Fig.1). A long-chain-length FA (LCFA) is attached to the amino group of sphingosine through an amide linkage, producing a ceramide, which can also serve as a precursor of glycolipids .
The alcohol group at carbon 1 of sphingosine is esterified to phosphorylcholine, producing sphingomyelin, the only significant sphingophospholipid in humans. Sphingomyelin is an important constituent of the myelin sheath of nerve fibers. [Note: The myelin sheath is a layered, membranous structure that insulates and protects neuronal axons of the central nervous system (CNS).]
Figure 1 : Structure of sphingomyelin, showing sphingosine (in green box) and ceramide components (in dashed box). = phosphate.
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علامات بسيطة في جسدك قد تنذر بمرض "قاتل"
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أول صور ثلاثية الأبعاد للغدة الزعترية البشرية
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مكتبة أمّ البنين النسويّة تصدر العدد 212 من مجلّة رياض الزهراء (عليها السلام)
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