Glycogen Granules-Liver

Glycogen is a typical inclusion in liver cells. It forms electron-dense, irregularly shaped granules ( β-particles) 1 with diameters of 20–40 nm. β-Particles aggregate to form α-particles with diameters approaching 200 nm. β-Particles of ten assemble and form rosette structures with diameters of 0.2–0.4 mm.  This figure shows two liver cells with osmiophilic glycogen granules 1 and numerous mitochondria 2 .

1 Glycogen granules                  4 Endothelial cell with nucleus

2 Mitochondria                         5 Disse’s space (perisinusoidal space)

3 Lumen of a liver sinus           6 Hepatocyte microvilli

References

Kuehnel, W.(2003). Color Atlas of Cytology, Histology, and Microscopic Anatomy. 4^th edition . Institute of Anatomy Universitätzu Luebeck Luebeck, Germany . Thieme Stuttgar t · New York .