Extraepithelial Glands-Holocrine Sebaceous Glands

Sebaceous glands consist of bulbous multilayered epithelium cones, termed sebaceous bulbs or sacs, which lack a luminal space. The neck of the main bulb opens to the hair shaft. The cells inside the bulb grow larger, produce sebum and consequently, change into sebum cells 2 . Their nuclei then die ( apoptosis). In the usual preparations use d for teaching purposes, the fat droplets are removed. This leads to more and more vacuoles in the cells at the center. While producing the secretory product , the cells die and are extrude d together with the secretory material (sebum): holocrine extrusion, holocytosis, (cell lysis). New cells arrive from a supply line, which start at the peripheral cell layer (substitute cells, basal cells) 3 .

1 Sebum in the neck of the gland

2 Sebaceous gland cells

3 Peripheral cells (substitute cells, basal cells)

4 Dense regular connective tissue

Stain: azan; magnification: × 65

References

Kuehnel, W.(2003). Color Atlas of Cytology, Histology, and Microscopic Anatomy. 4^th edition . Institute of Anatomy Universitätzu Luebeck Luebeck, Germany . Thieme Stuttgar t · New York .