An mRNA vaccine has been developed against 20 known subtypes of influenza virus. Initial tests conducted on animals showed that the vaccine reduced signs of disease and protected these animals from death. The effects of this vaccine appeared when these animals were exposed to influenza viruses unrelated to the viruses used to make the vaccine.
The study indicates that the vaccine may provide broad protection against all strains of influenza, including deadly strains. A vaccine could be a great tool in the medical arsenal given the risk of influenza, especially during pandemics, and the deaths caused by seasonal influenza.
“The basic idea of the vaccine is to give people the basic level that makes their immune memory able to know the various strains of influenza, so the number of patients and deaths will be much lower than it was when any event or influenza pandemic occurred,” said the study’s senior author Dr. Scott Hensley, professor of microbiology at Perelman College of Medicine.
The vaccine uses mRNA technology that has shown success when used in COVID-19 vaccines.
The team was keen to test this vaccine on humans. Human clinical trials are now being designed to see how this vaccine works when given to people. If successful, this vaccine could be used to reduce the risk of contracting the influenza virus in all age groups.
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